mouse GRINL1A Over-expression AAV

Name 
AAV-m-GRINL1A
Cat No 
AAV-260774
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Polr2m.

AAV-260774
AAV-m-GRINL1A

Ready-to-use AAV expressing Mouse Polr2m (polymerase (RNA) II (DNA directed) polypeptide M). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA407243; AA408799; AI303746; AW553238; D9Wsu138e; Grinl1a; mKIAA4185
Description (Vector)
Isoform 1 appears to be a stable component of the Pol II(G) complex form of RNA polymerase II (Pol II). Pol II synthesizes mRNA precursors and many functional non-coding RNAs and is the central component of the basal RNA polymerase II transcription machinery. Isoform 1 may play a role in the Mediator complex-dependent regulation of transcription activation. Isoform 1 acts in vitro as a negative regulator of transcriptional activation; this repression is relieved by the Mediator complex, which restores Pol II(G) activator-dependent transcription to a level equivalent to that of Pol II.
Gene ID
28015
Gene Name (Vector)
polymerase (RNA) II (DNA directed) polypeptide M
Gene Symbol
Polr2m
ORF Size (aa)
1101
ORF Size (bp)
1101 bp
RefSeq ID
NM_178602
RefSeq Synonyms
NM_178602, NM_001164793, BC062199, BC018502,
Species
mouse
UniGene ID
Mm.21094

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.