mouse GPR120 Over-expression AAV

Name 
AAV-m-GPR120
Cat No 
AAV-260561
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ffar4.

AAV-260561
AAV-m-GPR120

Ready-to-use AAV expressing Mouse Ffar4 (free fatty acid receptor 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI552415; Gpr120; Gpr129; GT01; KPG_013; O3far1; Pgr4
Description (Vector)
Receptor for medium and long-chain free fatty acid (FAA). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1 dependent effect but independent of G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediates the taste of fatty acids (By similarity).
Gene ID
107221
Gene Name (Vector)
free fatty acid receptor 4
Gene Symbol
Ffar4
ORF Size (aa)
1086
ORF Size (bp)
1086 bp
RefSeq ID
NM_181748
RefSeq Synonyms
NM_181748, BC053698,
Species
mouse
UniGene ID
Mm.35288

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.