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mouse GCH1 Over-expression AAV

Name 
AAV-m-GCH1
Cat No 
AAV-259978
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Gch1.

AAV-259978
AAV-m-GCH1

Ready-to-use AAV expressing Mouse Gch1 (GTP cyclohydrolase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Gch; GTP-CH; GTPCH
Description (Vector)
Positively regulates nitric oxide synthesis in umbilical vein endothelial cells (HUVECs). May be involved in dopamine synthesis. May modify pain sensitivity and persistence. Isoform GCH-1 is the functional enzyme, the potential function of the enzymatically inactive isoforms remains unknown.
Gene ID
14528
Gene Name (Vector)
GTP cyclohydrolase 1
Gene Symbol
Gch1
ORF Size (aa)
726
RefSeq ID
NM_008102
RefSeq Synonyms
NM_008102, BC069921, BC005643,
Species
mouse
UniGene ID
Mm.10651

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.