mouse FCHO2 Over-expression AAV

Name 
AAV-m-FCHO2
Cat No 
AAV-259292
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Fcho2.

AAV-259292
AAV-m-FCHO2

Ready-to-use AAV expressing Mouse Fcho2 (FCH domain only 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5832424M12Rik; AA387320
Description (Vector)
Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.
Gene ID
218503
Gene Name (Vector)
FCH domain only 2
Gene Symbol
Fcho2
ORF Size (aa)
2358
ORF Size (bp)
2358 bp
RefSeq ID
NM_172591
RefSeq Synonyms
NM_172591, BC052456,
Species
mouse
UniGene ID
Mm.23928

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.