mouse FAS Over-expression AAV

Name 
AAV-m-FAS
Cat No 
AAV-259165
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Fas.

AAV-259165
AAV-m-FAS

Ready-to-use AAV expressing Mouse Fas (Fas (TNF receptor superfamily member 6)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI196731; APO1; APT1; CD95; lpr; TNFR6; Tnfrsf6
Description (Vector)
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Gene ID
14102
Gene Name (Vector)
Fas (TNF receptor superfamily member 6)
Gene Symbol
Fas
ORF Size (aa)
984
RefSeq ID
NM_007987
RefSeq Synonyms
NM_007987, NM_001146708, BC061160,
Species
mouse
UniGene ID
Mm.1626

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.