mouse FAM175A Over-expression AAV

Name 
AAV-m-FAM175A
Cat No 
AAV-259024
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Fam175a.

AAV-259024
AAV-m-FAM175A

Ready-to-use AAV expressing Mouse Fam175a (family with sequence similarity 175, member A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
3830405G04Rik; 5630400M01Rik; AI506069; AL024423; AV118690; Ccdc98
Description (Vector)
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as a central scaffold protein that assembles the various components of the BRCA1-A complex and mediates the recruitment of BRCA1.
Gene ID
70681
Gene Name (Vector)
family with sequence similarity 175, member A
Gene Symbol
Fam175a
ORF Size (aa)
897
ORF Size (bp)
897 bp
RefSeq ID
NM_172405
RefSeq Synonyms
NM_172405, BC029845,
Species
mouse
UniGene ID
Mm.221269

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.