mouse EDEM2 Over-expression AAV

Name 
AAV-m-EDEM2
Cat No 
AAV-257751
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Edem2.

AAV-257751
AAV-m-EDEM2

Ready-to-use AAV expressing Mouse Edem2 (ER degradation enhancer, mannosidase alpha-like 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
9530090G24Rik; AI327354
Description (Vector)
Involved in endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity. Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
Gene ID
108687
Gene Name (Vector)
ER degradation enhancer, mannosidase alpha-like 2
Gene Symbol
Edem2
ORF Size (aa)
1734
ORF Size (bp)
1734 bp
RefSeq ID
NM_145537
RefSeq Synonyms
NM_145537, BC008268,
Species
mouse
UniGene ID
Mm.273706

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.