mouse DPH1 Over-expression AAV

Name
AAV-m-DPH1

Cat No
AAV-257409

Availability
4-5 weeks

This is an AAV expressing Mouse Dph1.

AAV-257409

AAV-m-DPH1

Ready-to-use AAV expressing Mouse Dph1 (diphthamide biosynthesis 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

2310011M22Rik; 4930488F09Rik; AW551873; Dph2l1; Ovca1

Description (Vector)

Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. When overexpressed, suppresses colony formation ability and growth rate of ovarian cancer cells. Acts also as a tumor suppressor in lung and breast cancers (By similarity). Plays a role in embryonic growth, organogenesis and postnatal survival (By similarity).

Gene ID

116905

Gene Name (Vector)

diphthamide biosynthesis 1

Gene Symbol

Dph1

ORF Size (aa)

1314

ORF Size (bp)

1314 bp

RefSeq ID

NM_144491

RefSeq Synonyms

NM_144491, BC152729,

Species

mouse

UniGene ID

Mm.41496

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.