mouse CTNNA1 Over-expression AAV

Name 
AAV-m-CTNNA1
Cat No 
AAV-256312
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Ctnna1.

AAV-256312
AAV-m-CTNNA1

Ready-to-use AAV expressing Mouse Ctnna1 (catenin (cadherin associated protein), alpha 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2010010M04Rik; AA517462; AI988031; Catna1
Description (Vector)
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
Gene ID
12385
Gene Name (Vector)
catenin (cadherin associated protein), alpha 1
Gene Symbol
Ctnna1
ORF Size (aa)
2721
ORF Size (bp)
2721 bp
RefSeq ID
NM_009818
RefSeq Synonyms
NM_009818, BC105576, BC068316, BC048163,
Species
mouse
UniGene ID
Mm.18962

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.