mouse CNGA3 Over-expression AAV

Name 
AAV-m-CNGA3
Cat No 
AAV-255744
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Cnga3.

AAV-255744
AAV-m-CNGA3

Ready-to-use AAV expressing Mouse Cnga3 (cyclic nucleotide gated channel alpha 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CNG3
Description (Vector)
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.
Gene ID
12790
Gene Name (Vector)
cyclic nucleotide gated channel alpha 3
Gene Symbol
Cnga3
ORF Size (aa)
1896
ORF Size (bp)
1896 bp
RefSeq ID
NM_009918
RefSeq Synonyms
NM_009918, NM_001282010, BC049145, BC035272,
Species
mouse
UniGene ID
Mm.214224

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.