mouse CD276 Over-expression AAV

Name 
AAV-m-CD276
Cat No 
AAV-254982
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Cd276.

AAV-254982
AAV-m-CD276

Ready-to-use AAV expressing Mouse Cd276 (CD276 antigen). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
6030411F23Rik; AU016588; B7h3; B7RP-2
Description (Vector)
CD276 may participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.
Gene ID
102657
Gene Name (Vector)
CD276 antigen
Gene Symbol
Cd276
ORF Size (aa)
951
ORF Size (bp)
951 bp
RefSeq ID
NM_133983
RefSeq Synonyms
NM_133983, BC056608, BC019436,
Species
mouse
UniGene ID
Mm.5356

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.