mouse CAV2 Over-expression AAV

Name 
AAV-m-CAV2
Cat No 
AAV-254588
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Cav2.

AAV-254588
AAV-m-CAV2

Ready-to-use AAV expressing Mouse Cav2 (caveolin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI447843
Description (Vector)
CAV2 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).
Gene ID
12390
Gene Name (Vector)
caveolin 2
Gene Symbol
Cav2
ORF Size (aa)
489
ORF Size (bp)
489 bp
RefSeq ID
NM_016900
RefSeq Synonyms
NM_016900, NM_001277756, BC023095,
Species
mouse
UniGene ID
Mm.396075

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.