mouse CASQ2 Over-expression AAV

Name 
AAV-m-CASQ2
Cat No 
AAV-254569
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Casq2.

AAV-254569
AAV-m-CASQ2

Ready-to-use AAV expressing Mouse Casq2 (calsequestrin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA033488; AW146219; cCSQ; Csq2; ESTM52
Description (Vector)
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. The release of calcium bound to calsequestrin through a calcium release channel triggers muscle contraction. The skeletal muscle isoform (CASQ1) binds around 80 Ca(2+) ions, while the cardiac isoform (CASQ2) binds approximately 60 Ca(2+) ions.
Gene ID
12373
Gene Name (Vector)
calsequestrin 2
Gene Symbol
Casq2
ORF Size (aa)
1248
ORF Size (bp)
1248 bp
RefSeq ID
NM_009814
RefSeq Synonyms
NM_009814, BC140959, BC137668, BC092229,
Species
mouse
UniGene ID
Mm.15343

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.