mouse CASP7 Over-expression AAV

Name 
AAV-m-CASP7
Cat No 
AAV-254561
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Casp7.

AAV-254561
AAV-m-CASP7

Ready-to-use AAV expressing Mouse Casp7 (caspase 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI314680; caspase-7; CMH-1; ICE-IAP3; mCASP-7; Mch3
Description (Vector)
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp- -Gly-217' bond. Overexpression promotes programmed cell death.
Gene ID
12369
Gene Name (Vector)
caspase 7
Gene Symbol
Casp7
ORF Size (aa)
912
ORF Size (bp)
912 bp
RefSeq ID
NM_007611
RefSeq Synonyms
NM_007611, BC005428,
Species
mouse
UniGene ID
Mm.35687

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.