mouse APH1A Over-expression AAV

Name 
AAV-m-APH1A
Cat No 
AAV-254511
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Aph1a.

AAV-254511
AAV-m-APH1A

Ready-to-use AAV expressing Mouse Aph1a (aph1 homolog A, gamma secretase subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
6530402N02Rik; APH-1a
Description (Vector)
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
Gene ID
226548
Gene Name (Vector)
aph1 homolog A, gamma secretase subunit
Gene Symbol
Aph1a
ORF Size (aa)
744
ORF Size (bp)
744 bp
RefSeq ID
NM_146104
RefSeq Synonyms
NM_146134, NM_146104, BC057865, BC024111, BC012406,
Species
mouse
UniGene ID
Mm.306954

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.