mouse CABLES1 Over-expression AAV
This is an AAV expressing Mouse Cables1.
AAV-254346
AAV-m-CABLES1
Ready-to-use AAV expressing Mouse Cables1 (CDK5 and Abl enzyme substrate 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cables; ik3-1
Description (Vector)
Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity).
Gene ID
63955
Gene Name (Vector)
CDK5 and Abl enzyme substrate 1
Gene Symbol
Cables1
ORF Size (aa)
1707
ORF Size (bp)
1707 bp
RefSeq ID
NM_022021
RefSeq Synonyms
NM_022021, NM_001146287, BC150714, BC145142,
Species
mouse
UniGene ID
Mm.40717
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.