mouse BRAP Over-expression AAV

Name
AAV-m-BRAP

Cat No
AAV-254068

Availability
4-5 weeks

This is an AAV expressing Mouse Brap.

AAV-254068

AAV-m-BRAP

Ready-to-use AAV expressing Mouse Brap (BRCA1 associated protein). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

3010002G07Rik; BRAP2; IMP

Description (Vector)

Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.

Gene ID

72399

Gene Name (Vector)

BRCA1 associated protein

Gene Symbol

Brap

ORF Size (aa)

1125

ORF Size (bp)

1125 bp

RefSeq ID

NM_028227

RefSeq Synonyms

NM_028227, NM_001289544, NM_001289543, BC038490,

Species

mouse

UniGene ID

Mm.153372

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.