mouse BAX Over-expression AAV

Name 
AAV-m-BAX
Cat No 
AAV-253636
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Bax.

AAV-253636
AAV-m-BAX

Ready-to-use AAV expressing Mouse Bax (BCL2-associated X protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Gene ID
12028
Gene Name (Vector)
BCL2-associated X protein
Gene Symbol
Bax
ORF Size (aa)
579
ORF Size (bp)
579 bp
RefSeq ID
NM_007527
RefSeq Synonyms
NM_007527, BC053380, BC018228,
Species
mouse
UniGene ID
Mm.19904

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.