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mouse TXNRD1 Over-expression AAV

Name 
AAV-m-TXNRD1
Cat No 
AAV-251525
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Txnrd1.

AAV-251525
AAV-m-TXNRD1

Ready-to-use AAV expressing Mouse Txnrd1 (thioredoxin reductase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
TR; TR1; TrxR1
Description (Vector)
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
Gene ID
50493
Gene Name (Vector)
thioredoxin reductase 1
Gene Symbol
Txnrd1
ORF Size (aa)
1494
ORF Size (bp)
1494 bp
RefSeq ID
NM_015762
RefSeq Synonyms
NM_015762, NM_001042523, NM_001042514, NM_001042513, BC037643,
Species
mouse
UniGene ID
Mm.210155

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.