mouse TXNRD1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-251525
Availability:
3-5 weeks
Name:
AAV-m-TXNRD1
This is an AAV expressing Mouse Txnrd1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Txnrd1
- Gene Name
- thioredoxin reductase 1
- Gene ID
- 50493
- Gene Synonyms
- TR; TR1; TrxR1
- ORF Size
- 1494 bp
- RefSeq#
- BC037643
- Gene Description
- Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
- UniGene ID
- Mm.210155
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