mouse 4930547N16RIK Over-expression AAV

Name
AAV-m-4930547N16RIK

Cat No
AAV-251165

Availability
4-5 weeks

This is an AAV expressing Mouse Parpbp.

AAV-251165

AAV-m-4930547N16RIK

Ready-to-use AAV expressing Mouse Parpbp (PARP1 binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

4930547N16Rik; AI503644; PARI

Description (Vector)

Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. Antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. Binds single-strand DNA and poly(A) homopolymers. Positively regulate the poly(ADP-ribosyl)ation activity of PARP1; however such function may be indirect.

Gene ID

75317

Gene Name (Vector)

PARP1 binding protein

Gene Symbol

Parpbp

ORF Size (aa)

1722

ORF Size (bp)

1722 bp

RefSeq ID

NM_029249

RefSeq Synonyms

NM_029249, BC070476,

Species

mouse

UniGene ID

Mm.179378

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.