mouse FBXO31 Over-expression AAV

Name
AAV-m-FBXO31

Cat No
AAV-250106

Availability
4-5 weeks

This is an AAV expressing Mouse Fbxo31.

AAV-250106

AAV-m-FBXO31

Ready-to-use AAV expressing Mouse Fbxo31 (F-box protein 31). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

1110003O08Rik; 2310046N15Rik; Fbx14; Fbxo14

Description (Vector)

Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. May act as a tumor suppressor.

Gene ID

76454

Gene Name (Vector)

F-box protein 31

Gene Symbol

Fbxo31

ORF Size (aa)

1050

ORF Size (bp)

1050 bp

RefSeq ID

NM_133765

RefSeq Synonyms

NM_133765, BC026929,

Species

mouse

UniGene ID

Mm.24829

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.