human GUCA1B Over-expression AAV

Name
AAV-h-GUCA1B

Cat No
AAV-230596

Availability
4-5 weeks

This is an AAV expressing Human GUCA1B.

AAV-230596

AAV-h-GUCA1B

Ready-to-use AAV expressing Human GUCA1B (guanylate cyclase activator 1B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

GCAP2; GUCA2; RP48

Description (Vector)

GUCA1B is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa.

Gene ID

2979

Gene Name (Vector)

guanylate cyclase activator 1B

Gene Symbol

GUCA1B

HGNC ID

HGNC:4679

ORF Size (aa)

603

RefSeq ID

NM_002098

RefSeq Synonyms

NM_002098, BC166640,

Species

human

UniGene ID

Hs.446529

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.