human AIDA Over-expression AAV

Name 
AAV-h-AIDA
Cat No 
AAV-229459
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human AIDA.

AAV-229459
AAV-h-AIDA

Ready-to-use AAV expressing Human AIDA (axin interactor, dorsalization associated). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
axin interaction partner and dorsalization antagonist; axin interactor, dorsalization-associated protein; C1orf80
Description (eCommerce)
Axin interactor and dorsalization-associated protein (AIDA) acts as a ventralizing factor during embryogenesis. By similarity AIDA is proposed to inhibit axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q96BJ3].
Gene ID
64853
Gene Name (eCommerce)
axin interactor, dorsalization associated
Gene Name (Vector)
axin interactor, dorsalization associated
Gene Symbol
AIDA
HGNC ID
HGNC:25761
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
921
ORF Size (bp)
921 bp
Protein Name (eCommerce)
Axin interactor, dorsalization-associated protein
RefSeq ID
NM_022831
RefSeq Synonyms
NM_022831, BC067805, BC015535,
Research Areas
JNK Signaling,Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
Axin interactor and dorsalization-associated protein (AIDA) acts as a ventralizing factor during embryogenesis. By similarity AIDA is proposed to inhibit axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q96BJ3].
UniGene ID
Hs.156625
UniProt ID (eCommerce)
Q96BJ3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.