human ZNF346 Over-expression AAV

Name 
AAV-h-ZNF346
Cat No 
AAV-228504
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ZNF346.

AAV-228504
AAV-h-ZNF346

Ready-to-use AAV expressing Human ZNF346 (zinc finger protein 346). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
double-stranded RNA-binding zinc finger protein JA; ZJA; Zjust another zinc finger protein; Zfp346; zinc finger protein 346
Description (eCommerce)
JAZ (just another zinc finger protein) is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. JAZ may be involved in cell growth and survival [taken from NCBI Entrez Gene (Gene ID: 23567)].
Description (Vector)
ZNF346 is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival.
Gene ID
23567
Gene Name (eCommerce)
zinc finger protein 346
Gene Name (Vector)
zinc finger protein 346
Gene Symbol
ZNF346
HGNC ID
HGNC:16403
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
885
Protein Name (eCommerce)
Zinc finger protein 346
RefSeq ID
NM_012279
RefSeq Synonyms
NM_012279, NM_001308223, NM_001308221, NM_001308219, NM_001308218, NM_001308216, NM_001308215, NM_001308214, NM_001308213, BC007775,
Research Areas
Apoptosis,RNA Binding,Zinc-finger
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
JAZ (just another zinc finger protein) is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. JAZ may be involved in cell growth and survival [taken from NCBI Entrez Gene (Gene ID: 23567)].
UniGene ID
Hs.484259
UniProt ID (eCommerce)
Q9UL40

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.