human YWHAB Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-228001
Availability:
3-5 weeks
Name:
AAV-h-YWHAB
This is an AAV expressing Human YWHAB.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- YWHAB
- Gene Name
- tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
- Gene ID
- 7529
- Gene Synonyms
- GW128; HEL-S-1; HS1; KCIP-1; YWHAA
- ORF Size
- 741 bp
- RefSeq#
- BC001359
- Gene Description
- YWHAB encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.
- UniGene ID
- Hs.643544
- HGNC ID
- HGNC:12849
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