human XRCC4 Over-expression AAV

Name 
AAV-h-XRCC4
Cat No 
AAV-227926
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human XRCC4.

AAV-227926
AAV-h-XRCC4

Ready-to-use AAV expressing Human XRCC4 (X-ray repair cross complementing 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SSMED
Description (Vector)
XRCC4 functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants.
Gene ID
7518
Gene Name (Vector)
X-ray repair cross complementing 4
Gene Symbol
XRCC4
HGNC ID
HGNC:12831
ORF Size (aa)
933
RefSeq ID
NM_022406
RefSeq Synonyms
NM_022550, NM_022406, NM_003401, NM_001318013, NM_001318012, BC016314, BC005259,
Species
human
UniGene ID
Hs.567359

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.