human WDR8 Over-expression AAV

Name
AAV-h-WDR8

Cat No
AAV-227734

Availability
4-5 weeks

This is an AAV expressing Human WRAP73.

AAV-227734

AAV-h-WDR8

Ready-to-use AAV expressing Human WRAP73 (WD repeat containing, antisense to TP73). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

WDR8

Description (Vector)

WRAP73 encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Studies of the related mouse protein suggest that the encoded protein may play a role in the process of ossification.

Gene ID

49856

Gene Name (Vector)

WD repeat containing, antisense to TP73

Gene Symbol

WRAP73

HGNC ID

HGNC:12759

ORF Size (aa)

1383

ORF Size (bp)

1383 bp

RefSeq ID

NM_017818

RefSeq Synonyms

NM_017818, BC086311,

Species

human

UniGene ID

Hs.31714

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.