human WDR45 Over-expression AAV

Name 
AAV-h-WDR45
Cat No 
AAV-227683
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human WDR45.

AAV-227683
AAV-h-WDR45

Ready-to-use AAV expressing Human WDR45 (WD repeat domain 45). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
JM5; NBIA4; NBIA5; WDRX1; WIPI-4; WIPI4
Description (Vector)
WDR45 encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR45 has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined.
Gene ID
11152
Gene Name (Vector)
WD repeat domain 45
Gene Symbol
WDR45
HGNC ID
HGNC:28912
ORF Size (aa)
1083
RefSeq ID
NM_007075
RefSeq Synonyms
NM_007075, NM_001029896, BC069206, BC003037, BC000464,
Species
human
UniGene ID
Hs.632807

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.