human VDAC3 Over-expression AAV

Name 
AAV-h-VDAC3
Cat No 
AAV-227455
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human VDAC3.

AAV-227455
AAV-h-VDAC3

Ready-to-use AAV expressing Human VDAC3 (voltage dependent anion channel 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HD-VDAC3; VDAC-3
Description (Vector)
VDAC3 encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene.
Gene ID
7419
Gene Name (Vector)
voltage dependent anion channel 3
Gene Symbol
VDAC3
HGNC ID
HGNC:12674
ORF Size (aa)
852
RefSeq ID
NM_005662
RefSeq Synonyms
NM_005662, NM_001135694, BC056870,
Species
human
UniGene ID
Hs.699301

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.