human USP8 Over-expression AAV

Name 
AAV-h-USP8
Cat No 
AAV-227347
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human USP8.

AAV-227347
AAV-h-USP8

Ready-to-use AAV expressing Human USP8 (ubiquitin specific peptidase 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
deubiquitinating enzyme 8; hUBPy; HumORF8; PITA4; SPG59; ubiquitin carboxyl-terminal hydrolase 8; ubiquitin isopeptidase Y; Ubiquitin thioesterase 8; ubiquitin thiolesterase 8; ubiquitin-specific-processing protease 8; UBPY
Description (eCommerce)
USP8 (ubiquitin-specific processing protease 8) is also known as UBPY (ubiquitin isopeptidase Y). USP8 is a hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P40818].
Gene ID
9101
Gene Name (eCommerce)
ubiquitin specific peptidase 8
Gene Name (Vector)
ubiquitin specific peptidase 8
Gene Symbol
USP8
HGNC ID
HGNC:12631
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3357
ORF Size (bp)
3357 bp
Protein Name (eCommerce)
Ubiquitin carboxyl-terminal hydrolase 8
RefSeq ID
NM_005154
RefSeq Synonyms
NM_005154, NM_001283049, NM_001128611, NM_001128610, BC110590,
Research Areas
Cell Cycle,EGFR Signaling,Signal Transduction,Ubiquitination
Research Areas (Faceted)
signal_transduction,cell_biology,cell_cycle,genetics
Species
human
Target Sentence
USP8 (ubiquitin-specific processing protease 8) is also known as UBPY (ubiquitin isopeptidase Y). USP8 is a hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P40818].
UniGene ID
Hs.644563
UniProt ID (eCommerce)
P40818

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.