human TSHR Over-expression AAV

Name 
AAV-h-TSHR
Cat No 
AAV-226605
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TSHR.

AAV-226605
AAV-h-TSHR

Ready-to-use AAV expressing Human TSHR (thyroid stimulating hormone receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CHNG1; hTSHR-I; LGR3
Description (Vector)
TSHR is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
7253
Gene Name (Vector)
thyroid stimulating hormone receptor
Gene Symbol
TSHR
HGNC ID
HGNC:12373
ORF Size (aa)
2295
ORF Size (bp)
2295 bp
RefSeq ID
NM_000369
RefSeq Synonyms
NM_001142626, NM_001018036, NM_000369, BC156779, BC063613, BC009237,
Species
human
UniGene ID
Hs.160411

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.