human TSC22D1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-226579
Availability:
3-5 weeks
Name:
AAV-h-TSC22D1
This is an AAV expressing Human TSC22D1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- TSC22D1
- Gene Name
- TSC22 domain family member 1
- Gene ID
- 8848
- Gene Synonyms
- Ptg-2; TGFB1I4; TSC22
- ORF Size
- 3222 bp
- RefSeq#
- BC136482
- Gene Description
- TSC22D1 encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- UniGene ID
- Hs.507916
- HGNC ID
- HGNC:16826
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