human TRIM63 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-226473
Availability:
3-5 weeks
Name:
AAV-h-TRIM63
This is an AAV expressing Human TRIM63.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- TRIM63
- Gene Name
- tripartite motif containing 63
- Gene ID
- 84676
- Gene Synonyms
- IRF; MURF1; MURF2; RNF28; SMRZ
- ORF Size
- 1062 bp
- RefSeq#
- BC080529
- Gene Description
- TRIM63 encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.
- UniGene ID
- Hs.279709
- HGNC ID
- HGNC:16007
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