human TREX1 Over-expression AAV
This is an AAV expressing Human TREX1.
AAV-226376
AAV-h-TREX1
Ready-to-use AAV expressing Human TREX1 (three prime repair exonuclease 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AGS1; CRV; DRN3; HERNS
Description (Vector)
TREX1 encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants.
Gene ID
11277
Gene Name (Vector)
three prime repair exonuclease 1
Gene Symbol
TREX1
HGNC ID
HGNC:12269
ORF Size (aa)
1110
RefSeq ID
NM_033629
RefSeq Synonyms
NM_033629, NM_016381, NM_007248, BC160084, BC023630,
Species
human
UniGene ID
Hs.713742
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.