human TOP3A Over-expression AAV

Name 
AAV-h-TOP3A
Cat No 
AAV-226206
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TOP3A.

AAV-226206
AAV-h-TOP3A

Ready-to-use AAV expressing Human TOP3A (topoisomerase (DNA) III alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
TOP3; ZGRF7
Description (Vector)
TOP3A encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells.
Gene ID
7156
Gene Name (Vector)
topoisomerase (DNA) III alpha
Gene Symbol
TOP3A
HGNC ID
HGNC:11992
ORF Size (aa)
3006
ORF Size (bp)
3006 bp
RefSeq ID
NM_004618
RefSeq Synonyms
NM_004618, NM_001320759, BC051748,
Species
human
UniGene ID
Hs.592115

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.