human TMX4 Over-expression AAV

Name 
AAV-h-TMX4
Cat No 
AAV-226053
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TMX4.

AAV-226053
AAV-h-TMX4

Ready-to-use AAV expressing Human TMX4 (thioredoxin related transmembrane protein 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DJ971N18.2; PDIA14; protein disulfide isomerase family A, member 14; thioredoxin domain containing 13; thioredoxin domain-containing protein 13; thioredoxin-related transmembrane protein 4; TXNDC13
Description (eCommerce)
TMX4 is a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. TMX4 has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and C-terminal ASP/GLU-rich calcium binding domain. Unlike most members of this family, it lacks a C-terminal ER-retention sequence. TMX4 has been shown to have reductase activity in vitro. [provided by RefSeq, Jan 2017] [taken from NCBI Entrez Gene (Gene ID: 56255)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H1E5].
Gene ID
56255
Gene Name (eCommerce)
thioredoxin related transmembrane protein 4
Gene Name (Vector)
thioredoxin related transmembrane protein 4
Gene Symbol
TMX4
HGNC ID
HGNC:25237
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1050
ORF Size (bp)
1050 bp
Protein Name (eCommerce)
Thioredoxin-related transmembrane protein 4
RefSeq ID
NM_021156
RefSeq Synonyms
NM_021156, BC033787,
Research Areas
Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
TMX4 is a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. TMX4 has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and C-terminal ASP/GLU-rich calcium binding domain. Unlike most members of this family, it lacks a C-terminal ER-retention sequence. TMX4 has been shown to have reductase activity in vitro. [provided by RefSeq, Jan 2017] [taken from NCBI Entrez Gene (Gene ID: 56255)]. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H1E5].
UniGene ID
Hs.169358
UniProt ID (eCommerce)
Q9H1E5

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.