human TLX1 Over-expression AAV

Cat. No: AAV-225601

Availability: 3-5 weeks

Name: AAV-h-TLX1

This is an AAV expressing Human TLX1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TLX1
Gene Name: T-cell leukemia homeobox 1
Gene ID: 3195
Gene Synonyms: HOX11; TCL3
ORF Size: 774 bp
RefSeq#: BC130530
Gene Description: TLX1 encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants.
UniGene ID: Hs.89583
HGNC ID: HGNC:5056