human TLX1 Over-expression AAV

Name
AAV-h-TLX1

Cat No
AAV-225601

Availability
4-5 weeks

This is an AAV expressing Human TLX1.

AAV-225601

AAV-h-TLX1

Ready-to-use AAV expressing Human TLX1 (T-cell leukemia homeobox 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HOX11; TCL3

Description (Vector)

TLX1 encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants.

Gene ID

3195

Gene Name (Vector)

T-cell leukemia homeobox 1

Gene Symbol

TLX1

HGNC ID

HGNC:5056

ORF Size (aa)

774

RefSeq ID

NM_005521

RefSeq Synonyms

NM_005521, NM_001195517, BC130530,

Species

human

UniGene ID

Hs.89583

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.