human THOC7 Over-expression AAV

Name 
AAV-h-THOC7
Cat No 
AAV-225457
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human THOC7.

AAV-225457
AAV-h-THOC7

Ready-to-use AAV expressing Human THOC7 (THO complex 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
fSAP24; functional spliceosome-associated protein 24; hTREX30; Ngg1 interacting factor 3 like 1 binding protein 1; ngg1-interacting factor 3-like protein 1-binding protein 1; NIF3L1-binding protein 1; NIF3L1BP1; THO complex 7 homolog; THO complex subunit 7 homolog
Description (eCommerce)
THO complex subunit 7 homolog, encoded by the gene THOC7, is required for efficient export of polyadenylated RNA. THOC7 acts as a component of the THO subcomplex of the TREX complex. This complex is thought to couple mRNA transcription, processing and nuclear export [taken from UniProtKB (Entry: Q6I9Y2)].
Gene ID
80145
Gene Name (eCommerce)
THO complex 7
Gene Name (Vector)
THO complex 7
Gene Symbol
THOC7
HGNC ID
HGNC:29874
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
615
ORF Size (bp)
615 bp
Protein Name (eCommerce)
THO complex subunit 7 homolog
RefSeq ID
NM_025075
RefSeq Synonyms
NM_025075, NM_001285404, NM_001285387, BC065012,
Research Areas
Host-Virus Interactions,mRNA Processing,mRNA Splicing,mRNA transport,RNA Binding,RNA Processing,RNA Transport
Research Areas (Faceted)
infectious_disease,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
THO complex subunit 7 homolog, encoded by the gene THOC7, is required for efficient export of polyadenylated RNA. THOC7 acts as a component of the THO subcomplex of the TREX complex. This complex is thought to couple mRNA transcription, processing and nuclear export [taken from UniProtKB (Entry: Q6I9Y2)].
UniGene ID
Hs.288151
UniProt ID (eCommerce)
Q6I9Y2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.