human THNSL2 Over-expression AAV

Name 
AAV-h-THNSL2
Cat No 
AAV-225447
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human THNSL2.

AAV-225447
AAV-h-THNSL2

Ready-to-use AAV expressing Human THNSL2 (threonine synthase like 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SOFAT; THS2; TSH2
Description (Vector)
THNSL2 encodes a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants.
Gene ID
55258
Gene Name (Vector)
threonine synthase like 2
Gene Symbol
THNSL2
HGNC ID
HGNC:25602
ORF Size (aa)
1218
RefSeq ID
NM_018271
RefSeq Synonyms
NM_018271, NM_001244678, NM_001244676, BC064423,
Species
human
UniGene ID
Hs.516179

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.