human TDRD7 Over-expression AAV

Name
AAV-h-TDRD7

Cat No
AAV-225273

Availability
4-5 weeks

This is an AAV expressing Human TDRD7.

AAV-225273

AAV-h-TDRD7

Ready-to-use AAV expressing Human TDRD7 (tudor domain containing 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CATC4; epididymis secretory sperm binding protein; PCTAIRE2-binding protein; PCTAIRE2BP; TRAP; tudor domain-containing protein 7; tudor repeat associator with PCTAIRE 2; Tudor repeat associator with PCTAIRE-2

Description (eCommerce)

The Tudor domain-containing protein 7 encoded by the gene TDRD7 belongs to the Tudor family of proteins. This protein contains conserved Tudor domains and LOTUS domains. It is a component of RNA granules, which function in RNA processing. Mutations in this gene have been associated with cataract formation in mouse and human [taken from NCBI Entrez Gene (Gene ID: 23424)].

Description (Vector)

TDRD7 encodes a component of cytoplasmic RNA granules which are involved in determining the fate of mRNAs. Mutation in this gene has been associated with pediatric cataracts. Mutation of the similar gene in mice has been associated with cataracts, glaucoma and a block in spermatogenesis.

Gene ID

23424

Gene Name (eCommerce)

tudor domain containing 7

Gene Name (Vector)

tudor domain containing 7

Gene Symbol

TDRD7

HGNC ID

HGNC:30831

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

3297

ORF Size (bp)

3297 bp

Protein Name (eCommerce)

Tudor domain-containing protein 7

RefSeq ID

NM_014290

RefSeq Synonyms

NM_014290, NM_001302884, BC028694,

Research Areas

mRNA Binding,RNA Binding,Signal Transduction,Spermatogenesis

Research Areas (Faceted)

cell_biology,developmental_biology,genetics,signal_transduction,transcription_translation

Species

human

Target Sentence

The Tudor domain-containing protein 7 encoded by the gene TDRD7 belongs to the Tudor family of proteins. This protein contains conserved Tudor domains and LOTUS domains. It is a component of RNA granules, which function in RNA processing. Mutations in this gene have been associated with cataract formation in mouse and human [taken from NCBI Entrez Gene (Gene ID: 23424)].

UniGene ID

Hs.193842

UniProt ID (eCommerce)

Q8NHU6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.