human TBL1X Over-expression AAV

Name 
AAV-h-TBL1X
Cat No 
AAV-225130
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TBL1X.

AAV-225130
AAV-h-TBL1X

Ready-to-use AAV expressing Human TBL1X (transducin beta like 1X-linked). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EBI; SMAP55; TBL1
Description (Vector)
TBL1X has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.
Gene ID
6907
Gene Name (Vector)
transducin beta like 1X-linked
Gene Symbol
TBL1X
HGNC ID
HGNC:11585
ORF Size (aa)
1581
ORF Size (bp)
1581 bp
RefSeq ID
NM_005647
RefSeq Synonyms
NM_005647, NM_001139468, NM_001139467, NM_001139466, BC052304, BC032708,
Species
human
UniGene ID
Hs.495656

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.