human TBCKL Over-expression AAV

Name 
AAV-h-TBCKL
Cat No 
AAV-225125
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TBCK.

AAV-225125
AAV-h-TBCKL

Ready-to-use AAV expressing Human TBCK (TBC1 domain containing kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HSPC302; IHPRF3; TBC domain-containing protein kinase-like protein; TBCKL
Description (eCommerce)
TBC domain-containing protein kinase-like protein (TBCK) is a protein that contains a protein kinase domain, a Rhodanase-like domain and the Tre-2/Bub2/Cdc16 (TBC) domain. TBCK is thought to play a role in actin organization, cell growth and cell proliferation by regulating the mammalian target of the rapamycin (mTOR) signaling pathway. This protein may also be involved in the transcriptional regulation of the components of the mTOR comple [taken from NCBI Entrez Gene (Gene ID: 93627)].
Gene ID
93627
Gene Name (eCommerce)
TBC1 domain containing kinase
Gene Name (Vector)
TBC1 domain containing kinase
Gene Symbol
TBCK
HGNC ID
HGNC:28261
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2493
ORF Size (bp)
2493 bp
Protein Name (eCommerce)
TBC domain-containing protein kinase-like protein
RefSeq ID
NM_033115
RefSeq Synonyms
NM_033115, NM_001290768, NM_001163437, NM_001163436, NM_001163435, BC068496, BC009208,
Research Areas
Kinase/Phosphatase
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
TBC domain-containing protein kinase-like protein (TBCK) is a protein that contains a protein kinase domain, a Rhodanase-like domain and the Tre-2/Bub2/Cdc16 (TBC) domain. TBCK is thought to play a role in actin organization, cell growth and cell proliferation by regulating the mammalian target of the rapamycin (mTOR) signaling pathway. This protein may also be involved in the transcriptional regulation of the components of the mTOR comple [taken from NCBI Entrez Gene (Gene ID: 93627)].
UniGene ID
Hs.292986
UniProt ID (eCommerce)
Q8TEA7

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.