human TAP2 Over-expression AAV

Name 
AAV-h-TAP2
Cat No 
AAV-224967
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TAP2.

AAV-224967
AAV-h-TAP2

Ready-to-use AAV expressing Human TAP2 (transporter 2, ATP binding cassette subfamily B member). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ABC18; ABCB3; APT2; D6S217E; PSF-2; PSF2; RING11
Description (Vector)
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules.
Gene ID
6891
Gene Name (Vector)
transporter 2, ATP binding cassette subfamily B member
Gene Symbol
TAP2
HGNC ID
HGNC:44
ORF Size (aa)
2109
ORF Size (bp)
2109 bp
RefSeq ID
NM_000544
RefSeq Synonyms
NM_018833, NM_001290043, NM_000544, BC152839, BC002751,
Species
human
UniGene ID
Hs.502

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.