human TAOK3 Over-expression AAV

Name 
AAV-h-TAOK3
Cat No 
AAV-224965
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TAOK3.

AAV-224965
AAV-h-TAOK3

Ready-to-use AAV expressing Human TAOK3 (TAO kinase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CTCL-associated antigen HD-CL-09; cutaneous T-cell lymphoma-associated antigen HD-CL-09; dendritic cell-derived protein kinase; DPK; hKFC-A; JIK; JNK/SAPK-inhibitory kinase; jun kinase-inhibitory kinase; kinase from chicken homolog A; MAP3K18; serine/threonine-protein kinase TAO3; STE20-like kinase; thousand and one amino acid protein 3
Description (eCommerce)
Jun kinase-inhibitory kinase (JIK) is a member of the STE20 serine/threonine kinase family that has been demonstrated to negatively regulate c-jun N-terminal kinase. When overexpressed, JIK has been demonstrated to activate the ERK1/ERK2 (extracellular signal-regulated kinase) pathway.
Gene ID
51347
Gene Name (eCommerce)
TAO kinase 3
Gene Name (Vector)
TAO kinase 3
Gene Symbol
TAOK3
HGNC ID
HGNC:18133
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2697
ORF Size (bp)
2697 bp
Protein Name (eCommerce)
Serine/threonine-protein kinase TAO3
RefSeq ID
NM_016281
RefSeq Synonyms
NM_016281, NM_001346497, NM_001346496, NM_001346495, NM_001346494, NM_001346493, NM_001346492, NM_001346491, NM_001346490, NM_001346489, NM_001346488, NM_001346487, BC002756,
Research Areas
Cell Cycle,DNA Damage/Repair,JNK Signaling,Kinase/Phosphatase,MAPK Signaling,Mitochondrion,Signal Transduction
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,signal_transduction,transcription_translation
Species
human
Target Sentence
Jun kinase-inhibitory kinase (JIK) is a member of the STE20 serine/threonine kinase family that has been demonstrated to negatively regulate c-jun N-terminal kinase. When overexpressed, JIK has been demonstrated to activate the ERK1/ERK2 (extracellular signal-regulated kinase) pathway.
UniGene ID
Hs.644420
UniProt ID (eCommerce)
Q9H2K8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.