human T Over-expression AAV

Name 
AAV-h-T
Cat No 
AAV-224874
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human T.

AAV-224874
AAV-h-T

Ready-to-use AAV expressing Human T (T brachyury transcription factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
brachyury protein; protein T; SAVA; T; T brachyury transcription factor; T, brachyury homolog; T-box transcription factor T; TFT
Description (eCommerce)
TBXT is involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O15178].
Description (Vector)
T is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
6862
Gene Name (eCommerce)
T-box transcription factor T
Gene Name (Vector)
T brachyury transcription factor
Gene Symbol
T
HGNC ID
HGNC:11515
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1134
Protein Name (eCommerce)
Brachyury protein
RefSeq ID
NM_003181
RefSeq Synonyms
NM_003181, NM_001270484, BC098425,
Research Areas
Neurodevelopment,RNA Binding,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,developmental_biology,neurobiology,transcription_translation
Species
human
Target Sentence
TBXT is involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic site (called T site) and activates gene transcription when bound to such a site. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O15178].
UniGene ID
Hs.389457
UniProt ID (eCommerce)
O15178

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.