human SYTL2 Over-expression AAV

Name
AAV-h-SYTL2

Cat No
AAV-224864

Availability
4-5 weeks

This is an AAV expressing Human SYTL2.

AAV-224864

AAV-h-SYTL2

Ready-to-use AAV expressing Human SYTL2 (synaptotagmin like 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CHR11SYT; EXO4; PPP1R151; SGA72M; SLP2; SLP2A

Description (Vector)

SYTL2 is a synaptotagmin-like protein (SLP) that belongs to a C2 domain-containing protein family. The SLP homology domain (SHD) of this protein has been shown to specifically bind the GTP-bound form of Ras-related protein Rab-27A (RAB27A). This protein plays a role in RAB27A-dependent vesicle trafficking and controls melanosome distribution in the cell periphery. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene ID

54843

Gene Name (Vector)

synaptotagmin like 2

Gene Symbol

SYTL2

HGNC ID

HGNC:15585

ORF Size (aa)

2808

ORF Size (bp)

2808 bp

RefSeq ID

NM_032379

RefSeq Synonyms

NM_206930, NM_206929, NM_206928, NM_206927, NM_032943, NM_032379, NM_001289610, NM_001289609, NM_001289608, NM_001162953, NM_001162952, NM_001162951, BC144115, BC144114, BC136450,

Species

human

UniGene ID

Hs.369520

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.