human SYNJ2 Over-expression AAV

Name 
AAV-h-SYNJ2
Cat No 
AAV-224820
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SYNJ2.

AAV-224820
AAV-h-SYNJ2

Ready-to-use AAV expressing Human SYNJ2 (synaptojanin 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
inositol phosphate 5'-phosphatase 2; inositol polyphosphate-5-phosphatase H; INPP5H; phosphoinositide 5-phosphatase; synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2; synaptojanin-2
Description (eCommerce)
Synaptojanin 2 is a member of the inositol-polyphosphate 5-phosphatase family. Synaptojanin 2 interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis [taken from NCBI Entrez Gene (Gene ID: 4141)].
Description (Vector)
The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants.
Gene ID
8871
Gene Name (eCommerce)
synaptojanin 2
Gene Name (Vector)
synaptojanin 2
Gene Symbol
SYNJ2
HGNC ID
HGNC:11504
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2520
ORF Size (bp)
2520 bp
Protein Name (eCommerce)
Synaptojanin-2
RefSeq ID
NM_003898
RefSeq Synonyms
NM_003898, NM_001178088, BC043277,
Research Areas
Brain Development,Kinase/Phosphatase,Metabolism/Metabolic Process,Neurobiology,Neurodevelopment,RNA Binding
Research Areas (Faceted)
cell_biology,developmental_biology,metabolism,neurobiology,signal_transduction
Species
human
Target Sentence
Synaptojanin 2 is a member of the inositol-polyphosphate 5-phosphatase family. Synaptojanin 2 interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis [taken from NCBI Entrez Gene (Gene ID: 4141)].
UniGene ID
Hs.434494
UniProt ID (eCommerce)
O15056

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.