human STOM Over-expression AAV

Name 
AAV-h-STOM
Cat No 
AAV-224614
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human STOM.

AAV-224614
AAV-h-STOM

Ready-to-use AAV expressing Human STOM (stomatin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BND7; EPB7; EPB72; erythrocyte band 7 integral membrane protein; erythrocyte membrane protein band 7.2 (stomatin); erythrocyte surface protein band 7.2; protein 7.2b; Stomatin
Description (eCommerce)
Stomatin is a member of a highly conserved family of integral membrane proteins. Stomatin localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of stomatin is associated with hereditary stomatocytosis, a form of hemolytic anemi [taken from NCBI Entrez Gene (Gene ID: 2040)].
Description (Vector)
STOM encodes a member of a highly conserved family of integral membrane proteins. The encoded protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of the encoded protein is associated with hereditary stomatocytosis, a form of hemolytic anemia. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants.
Gene ID
2040
Gene Name (eCommerce)
stomatin
Gene Name (Vector)
stomatin
Gene Symbol
STOM
HGNC ID
HGNC:3383
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
867
Protein Name (eCommerce)
Erythrocyte band 7 integral membrane protein
RefSeq ID
NM_004099
RefSeq Synonyms
NM_198194, NM_004099, NM_001270527, NM_001270526, BC010703,
Research Areas
Cytoskeleton
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Stomatin is a member of a highly conserved family of integral membrane proteins. Stomatin localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of stomatin is associated with hereditary stomatocytosis, a form of hemolytic anemi [taken from NCBI Entrez Gene (Gene ID: 2040)].
UniGene ID
Hs.253903
UniProt ID (eCommerce)
P27105

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.