human SSPN Over-expression AAV

Name 
AAV-h-SSPN
Cat No 
AAV-224395
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SSPN.

AAV-224395
AAV-h-SSPN

Ready-to-use AAV expressing Human SSPN (sarcospan). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DAGA5; KRAG; NSPN; SPN1; SPN2
Description (Vector)
SSPN encodes a member of the dystrophin-glycoprotein complex (DGC). The DGC spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Two alternatively spliced transcript variants that encode different protein isoforms have been described.
Gene ID
8082
Gene Name (Vector)
sarcospan
Gene Symbol
SSPN
HGNC ID
HGNC:11322
ORF Size (aa)
732
RefSeq ID
NM_005086
RefSeq Synonyms
NM_005086, NM_001135823, BC062299,
Species
human
UniGene ID
Hs.183428

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.