human SREBF2 Over-expression AAV

Name 
AAV-h-SREBF2
Cat No 
AAV-224322
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SREBF2.

AAV-224322
AAV-h-SREBF2

Ready-to-use AAV expressing Human SREBF2 (sterol regulatory element binding transcription factor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bHLHd2; class D basic helix-loop-helix protein 2; SREBP2; SREBP-2; sterol regulatory element-binding protein 2; Sterol regulatory element-binding transcription factor 2
Description (eCommerce)
Sterol regulatory element binding transcription factor 2 (SREBP2) is a transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain [taken from NCBI Entrez Gene (Gene ID: 6721].
Description (Vector)
SREBF2 encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain.
Gene ID
6721
Gene Name (eCommerce)
sterol regulatory element binding transcription factor 2
Gene Name (Vector)
sterol regulatory element binding transcription factor 2
Gene Symbol
SREBF2
HGNC ID
HGNC:11290
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2046
ORF Size (bp)
2046 bp
Protein Name (eCommerce)
Sterol regulatory element-binding protein 2
RefSeq ID
NM_004599
RefSeq Synonyms
NM_004599, BC056158, BC051385,
Research Areas
Aging,Golgi Apparatus,Metabolism/Metabolic Process,Signal Transduction,Spermatogenesis,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,developmental_biology,metabolism,signal_transduction,transcription_translation
Species
human
Target Sentence
Sterol regulatory element binding transcription factor 2 (SREBP2) is a transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain [taken from NCBI Entrez Gene (Gene ID: 6721].
UniGene ID
Hs.443258
UniProt ID (eCommerce)
Q12772

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.